2009/11/12

Cannabis may prevent osteoporosis 大麻或能預防骨質疏鬆

◎鄭寺音

Researchers looking at the effects of cannabis on bones have found its impact varies dramatically with age. The study found that while the drug may reduce bone strength in the young, it could protect against osteoporosis, a weakening of the bones, in later life.

研究大麻對骨骼影響的研究人員發現,大麻的影響隨著年紀顯著不同。研究發現,雖然大麻可能讓年輕人的骨骼強度降低,但也可能預防往後出現骨骼強度減弱的骨質疏鬆。

The results were uncovered by a team at the University of Edinburgh who compared the drug’s effects on mice.

此一結果是由愛丁堡大學團隊,比較這種毒品對老鼠的影響後所發現。

The group found that cannabis can activate a molecule found naturally in the body that is key to the development of osteoporosis.

團隊發現,大麻可讓體內自然存在的一種分子活化,這種分子是導致骨質疏鬆的關鍵。

When the type 1 cannabinoid receptor (CB1) comes into contact with cannabis, it has an impact on bone regeneration. However, until now, it was not clear whether the drug had a positive or negative effect.

當第一型大麻素受體(CBI)與大麻接觸時,會對骨質再生有影響,但目前為止,並不清楚這種毒品是有正面還是負面的影響。

Researchers, funded by the Arthritis Research Campaign, investigated this using mice which lacked the CB1 receptor. The scientists then used compounds - similar to those in cannabis - that activated the CB1 receptor.

「關節炎研究運動」資助的研究人員,以缺乏大麻素受體的老鼠來進行調查,接著使用類似於大麻中的化合物,來活化大麻素受體。

They found that compounds increased the rate at which bone tissue was destroyed in the young. Despite this, the study also showed that the same compounds decreased bone loss in older mice and prevented the accumulation of fat in the bones, which is known to occur in humans with osteoporosis.

他們發現,化合物加速摧毀了年輕人的骨骼組織。儘管如此,這份研究也顯示,一些化合物降低年紀較大的老鼠的骨質流失,預防骨骼中的脂肪積累,骨質疏鬆患者的骨骼中已知會有脂肪積累現象。

新聞辭典

vary: 動詞,不同、變化。例句:My taste in classical music varies greatly, but I usually prefer Mozart or Brahms.(我對古典音樂的品味多變,不過通常我偏好莫札特或布拉姆斯。)

activate: 動詞,活化、刺激。例句:In order to activate market purchasing power, the two companies decided to lower the price to jointly sell some of the stock goods.(為了刺激市場購買力,這兩家公司決定降價,聯合促銷部分庫存。)

regeneration:名詞,再生,動詞為regenerate。

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