2009/04/30

Gene defect clue to male pill 基因缺陷為男性避孕藥提供線索

◎鄭寺音

A male contraceptive pill could be a step closer after US researchers identified a gene flaw linked to male infertility.

男性避孕藥的問世可能又更進了一步,因為美國研究人員找出與男性不孕相關的基因缺陷 。

The study of Iranian families found mutations in the CATSPER1 gene which controls a protein determining sperm movement.

這份針對伊朗家庭的研究,發現在CATSPER1這種基因中的突變。CATSPER1基因控制決定精子活動的蛋白質 。

Researchers say the finding could lead to treatments for infertile men - and potentially to a new contraceptive. UK researchers from the Medical Research Council Reproductive Biology Unit in have previously carried out surveys showing that men would be willing to take a contraceptive pill if one was available.

研究人員說,這項發現可能引領男性不孕的療法,也可能引導出一種新的避孕藥。英國醫療研究委員會生育生物學小組之前的調查顯示,如果有避孕藥,男性願意服用。

Condoms or a vasectomy are still the only male contraceptive choices.

男性避孕目前僅能靠保險套或輸精管結紮手術。

In this study, the researchers were looking at a population with high rates of disease-causing gene mutations to investigate genetic causes of deafness.

在這份研究中,研究人員研究帶有大量致病基因突變的人,來調查失聰的原因。

However, while they were collecting genetic information, the scientists discovered that two families had different DNA mutations in the CATSPER1 gene.

但當科學家收集基因資訊時,發現兩個家族的CATSPER1基因有不同的DNA突變。

新聞辭典

contraceptive:名詞,避孕藥,也作形容詞,避孕的。

flaw:名詞,缺陷、瑕疵。例句:There’s a fatal flaw in your reasoning.(你的論據有個致命的缺陷。)

infertile:形容詞,不孕的。例句:It has been estimated that one in eight couples is infertile.(據估計,八分之一配偶不孕。)

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